Anticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm

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Anticancer and apoptotic effects on cell proliferation of diosgenin isolated from Costus speciosus (Koen.) Sm

BACKGROUND Diosgenin, a naturally occurring steroid saponin found abundantly in C. speciosus, is a well-known precursor of various synthetic steroidal drugs that are extensively used in the pharmaceutical industry. METHODS The present study was conducted to evaluate the in vitro anticancer and apoptotic effects on cell proliferation of diosgenin isolated from C. speciosus (Koen.) Sm. RESULT...

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BACKGROUND Costus speciosus (Koen ex.Retz.) Sm (Costaceae) is an Indian ornamental plant which has long been used medicinally in traditional systems of medicine. The plant has been found to possess diverse pharmacological activities. Rhizomes are used to treat pneumonia, rheumatism, dropsy, urinary diseases, jaundice, skin diseases and leaves are used to treat mental disorders. METHOD Antibac...

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In-vitro Evaluation of Antioxidant Activity and Phenolic Content of Costus speciosus (Koen) J.E. Sm.

Costus speciosus (Koen) J.E. Sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. In the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by DPPH radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...

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In-vitro Evaluation of Antioxidant Activity and Phenolic Content of Costus speciosus (Koen) J.E. Sm.

Costus speciosus (Koen) J.E. Sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. In the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by DPPH radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...

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In-vitro Evaluation of Antioxidant Activity and Phenolic Content of Costus speciosus (Koen) J.E. Sm.

Costus speciosus (Koen) J.E. Sm. plant and its extracts are used for treatment of fever, snake bites, jaundice, and as a purgative, astringent and antibacterial agent. In the present study, an attempt has been made to evaluate in vitro antioxidant activity of different extracts of this plant by DPPH radical scavenging activity, total antioxidant capacity, nitric oxide scavenging activity, ion c...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2015

ISSN: 1472-6882

DOI: 10.1186/s12906-015-0836-8